Cytohesin-1
WebFeb 23, 2024 · Initially, CYTH1 was identified in a protein-protein interaction screen and found to interact specifically with the cytoplasmic part of the integrin β2 chain of LFA-1 … WebAug 18, 2003 · Cytoplasmic exchange factors for ARFs have been identified; they are called cytohesin-1 , ARNO (cytohesin-2) and GRP-1 (cytohesin-3) . Cytohesin-1 is a 47 …
Cytohesin-1
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WebTDR Targets ID: 578688 Echinococcus granulosus, cytohesin 1 Source Database / ID: GeneDB pI: 8.4469 Length (AA): 449 MW (Da): 50086 Paralog Number: 0 WebJul 26, 1996 · Cytohesin-1 contains two distinct polypeptide motifs found in previously described proteins ( Figure 1 A). The larger of these is the central SEC7 domain, which comprises roughly 200 amino acids and has been …
WebCytohesin-1 is a guanine nucleotide exchange factor for the GTPase ARF as well a regulator of cell adhesion. When injected into athymic mice, the transformed Rat-3 cell … WebMay 18, 2011 · There is particular interest in the mechanisms that control recruitment of the ARF guanine nucleotide exchange factors (GEFs) that mediate GTP binding to ARFs and, in the case of the cytohesin...
WebThis gene encodes a member of the cytohesin (CYTH) family, formerly known as the PSCD (pleckstrin homology, Sec7 and coiled-coil domains) family. Cytohesin family members have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. WebCytohesin 1 Antibody (MA1-060) in ICC/IF Immunofluorescence analysis of Cytohesin 1 was done on 70% confluent log phase HeLa cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 10 minutes, and blocked with 1% BSA for 1 hour at room temperature.
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WebThe presence of a Sec7 domain was noted by both groups, and cytohesin-1 GEP activity was soon reported. 23. The Sec7 domains of Gea2 24 and cytohesin-1 25 and −2 26 have the same overall conformation, with two domains of five α helices each, and amino acid sequences of all Sec7 domains have a high degree of identity. The active site is in ... how many old testament judges were thereWebMay 3, 2024 · The cytohesin proteins, consisting of four closely related members (cytohesins-1, -2, -3, and -4), are a subfamily of the Sec7 domain-containing guanine nucleotide exchange factors for ADP... how big is choctawhatchee bayWebJul 7, 1998 · Cytohesin-1 (B2–1) is a guanine nucleotide exchange factor for human ADP ribosylation factor (Arf) GTPases, which are important for vesicular protein trafficking and coatamer assembly in the cell. Cytohesin-1 also has been reported to promote cellular adhesion via binding to the β2 integrin cytoplasmic domain. how big is chipotleWebMar 21, 2024 · CYTH1 (Cytohesin 1) is a Protein Coding gene. Diseases associated with CYTH1 include Intellectual Developmental Disorder With Short Stature And Behavioral … how big is chippewa flowageWebImmunoprecipitation with a cytohesin-1 polyclonal antibody and blotting with cytohesin-1 specific mAbs revealed that cytohesin-1 is highly expressed in neutrophils. By PCR analysis of a human x rodent hybrid panel, the B2-1 … how many old people suffer from lonelinessWebMar 4, 1997 · Abstract. Cytohesin-1, a protein abundant in cells of the immune system, has been proposed to be a human homolog of the Saccharomyces cerevisiae Sec7 gene … how big is chino valley azWebCytohesin-1 is required for Schwann cell migration and that phosphorylation of cytohesin-1 at the Tyr-382 position is important for migration. Phosphorylation of cytohesin-1 by Fyn is required for initiation of myelination and the extent of myelination during development. how many olives in 100g